Protein Modification Reagents
![eMolecules Broadpharm / 14-(Azide-PEG4-ethylcarbamoyl)tridecanoic-t-butyl ester / 100mg / 784455327 / BP-29925 / 95.000 / / [null] / 558.761 / C28H54N4O7](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502473290.JPG-250.jpg)
eMolecules Broadpharm / 14-(Azide-PEG4-ethylcarbamoyl)tridecanoic-t-butyl ester / 100mg / 784455327 / BP-29925 / 95.000 / / [null] / 558.761 / C28H54N4O7
Broadpharm / 14-(Azide-PEG4-ethylcarbamoyl)tridecanoic-t-butyl ester / 100mg / 784455327 / BP-29925 / 95.000 / / [null] / 558.761 / C28H54N4O7
Medchemexpress LLC Dspe-peg5000-mal ammonium | 474922-22-0 | 98.4% | (C2H4O)nC51H92N1O13P.H3N | 50 MG
DSPE-PEG5000-Mal ammonium contains DSPE phospholipid and maleimide, making it suitable for preparing nanostructured lipid carriers. It is designed to enhance blood circulation time and provide higher stability for encapsulated agents. This product specifically contains PEG5000 and can be utilized in constructing immune liposomes for the delivery of brain drugs.
- Used to prepare nanostructured lipid carriers
- Enhances blood circulation time
- Provides higher stability for encapsulated agents
- Suitable for brain drug delivery
Medchemexpress LLC BODIPY FL alkyne 10mg | 302795-84-2 | 10 MG
BODIPY FL alkyne is a green-fluorescent borondipyrromethene dye with a terminal alkyne group for copper-catalyzed click conjugation. It is bright and photostable, emits in the fluorescein (FAM) channel, and is supplied as a purified solid suitable for labeling, probe synthesis, and fluorescence imaging.
- Molecular formula C17H18BF2N3O; molecular weight 329.15.
- Excitation ~495 nm; emission ~516 nm.
- High purity (≈98.2%) by HPLC/1H NMR.
- Terminal alkyne compatible with copper(I)-catalyzed azide-alkyne cycloaddition.
- Available in small milligram quantities for research use.
Cayman Chemical AzIdo-dPEG7-amIn 5mg
A heterobifunctional PEGylated linker; contains a reactive NH2 end group, as well as an azide functional group for use in click chemistry reactions; has been used as a linker in the synthesis of bivalent mTOR inhibitors
Medchemexpress LLC Mal-amido-PEG5-C2-NHS ester | 1315355-92-0 | >98.0% | 557.55 g·mol⁻1 | C24H35N3O12 | 250 MG
Mal-amido-PEG5-C2-NHS ester is a non-cleavable antibody-drug conjugate (ADC) linker containing a maleimide group and an N-hydroxysuccinimide (NHS) ester. The NHS ester labels primary amines on proteins and amine-modified oligonucleotides, while the maleimide provides a thiol-reactive handle; the PEG5 spacer improves solubility and spacing for bioconjugation.
- Non-cleavable linker with maleimide and NHS reactive groups.
- PEG5 spacer increases solubility and reduces steric hindrance.
- NHS ester reacts with primary amines for labeling.
- Maleimide enables thiol-selective conjugation.
- High purity suitable for research bioconjugation (≥98.0%).
Medchemexpress LLC Cyanine5 alkyne (Alkyne-Cy5) | 1223357-57-0 | 98.2% | 556.18 | 50 MG
Cyanine5 alkyne (Alkyne-Cy5) is a fluorescent dye utilized for labeling azide proteins, enabling analysis of post-translational modifications like glycosylation. It also functions as a mitochondrial OXPHOS inhibitor, hindering the growth of cancer stem cells (CSCs). This compound is a click chemistry reagent, featuring an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules.
- Enables analysis of post-translational modifications like glycosylation
- Functions as a mitochondrial OXPHOS inhibitor
- Hinders the growth of cancer stem cells (CSCs)
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Significantly inhibits 3D mammosphere formation in MCF7 cells
Kyfora Bio DSPE PEG 2000 Amine 10 MG
DSPE-PEG(2000)-amine is DSPE (a phospholipid) functionalized with PEG2000. It can be used in the synthesis of solid lipid and thermosensitive nanoparticles, as well as for encapsulation of hydrophobic drugs. Functionalization with PEG prevents increases bioavailability and prevents opsonization. It has been used for the delivery of anticancer agents as well as other drug cargo. Key application(s): Drug delivery
Medchemexpress LLC Endo-BCN-PEG8-NHS ester | 1608140-48-2 | 95.0% | 714.80 | 50 MG
Endo-BCN-PEG8-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring a BCN group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This product is utilized in leveraging the intracellular ubiquitin-proteasome system for selective protein degradation.
- PEG-based PROTAC linker
- Functions as a click chemistry reagent
- Contains a BCN group for strain-promoted alkyne-azide cycloaddition (SPAAC)
- Facilitates synthesis of PROTACs
- Supports targeted protein degradation
Medchemexpress LLC 4,7,10,13-Tetraoxahexadecanediamide, N1,N16-bis[3-(11,12-didehydrodibenz[b,f]azocin-5(6H) | 2182601-68-7 | 97.4% | 100 MG
DBCO-PEG4-DBCO is a versatile PEG-based PROTAC linker used in the synthesis of PROTACs. It also serves as a cleavable ADC linker for antibody-drug conjugate (ADC) synthesis. As a click chemistry reagent, it features a DBCO group that enables strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules.
- Functions as a PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Serves as a cleavable ADC linker
- Enables synthesis of antibody-drug conjugates (ADCs)
- Acts as a click chemistry reagent
- Contains a DBCO group for SPAAC reactions
Medchemexpress LLC Nhpi-peg4-c2-nhs ester | 1415328-95-8 | MFCD28155511 | 98.9% | 508.48 g/mol | C23H28N2O11 | 1 G
NHPI-PEG4-C2-NHS ester is a PEG-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is supplied for research use and has a molecular weight of 508.48 g/mol and formula C23H28N2O11. Store the pure material at -20°C; observe low-temperature storage for solutions.
Medchemexpress LLC m-PEG20-alcohol 1g
m-PEG20-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Medchemexpress LLC Pomalidomide Solid Solv Recons | HY-10984-SOLIDSOLVENT10MM
Pomalidomide Solid Solv Recons
![eMolecules Broadpharm / DBCO-PEG2-PFP ester / 100mg / 448298236 / BP-24326 / 98.000 / 2304558-23-2 / [null] / 630.568 / C32H27F5N2O6](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502477062.JPG-250.jpg)
eMolecules Broadpharm / DBCO-PEG2-PFP ester / 100mg / 448298236 / BP-24326 / 98.000 / 2304558-23-2 / [null] / 630.568 / C32H27F5N2O6
Broadpharm / DBCO-PEG2-PFP ester / 100mg / 448298236 / BP-24326 / 98.000 / 2304558-23-2 / [null] / 630.568 / C32H27F5N2O6
Medchemexpress LLC DSPE-PEG-amine (ammonium) | 474922-26-4 | 99.5% | 1000 (average) | (C2H4O)nN2O10P.NH3 | 50 MG
DSPE-PEG-Amine, MW 1000 (ammonium) is an amine-terminated PEGylated phospholipid used to functionalize liposomes and nanoparticle surfaces for bioconjugation and targeted delivery. The terminal primary amine enables covalent coupling to aldehydes and activated esters, facilitating stable surface modification.
- Amine-terminated PEGylated phospholipid suitable for liposome and nanoparticle functionalization.
- Average molecular weight ~1000, providing a balance between hydrophilicity and anchoring.
- High purity (~99.5%) for reproducible conjugation and formulation performance.
- White to off-white solid, convenient for storage and handling.
- Storage: store sealed at -20°C; in solvent, -80°C (6 months) or -20°C (1 month).
- Terminal primary amine enables covalent conjugation to aldehydes or activated esters.
eMolecules AA Blocks LLC Fmoc-N-amido-PEG4-acid 100mg 410171201 AA0038KJ 0 000 557756-85-1 MFCD06656472 487 549 C26H33NO8
AA Blocks LLC Fmoc-N-amido-PEG4-acid 100mg 410171201 AA0038KJ 0 000 557756-85-1 MFCD06656472 487 549 C26H33NO8